Santa Maria Suites Resort

1401 Simonton Street, Key West, FL, 33040
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| 5.0Based on 2404 Reviews
For your protection, this hotel is following certain sanitization standards and procedures.
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Need help booking? 1-800-679-9738

Hotel Details

Our Key West hotel stands apart from other Key West beach resorts. Experience a truly sophisticated and contemporary Key West resort when you choose The Santa Maria Suites Resort. Barely a block from the Atlantic Ocean and Duval Street, the elegantly refined all-suites Key West luxury accommodations are nothing short of breathtaking. The charm of this Key West along with spacious Key West hotel suites and gracious amenities await you at our Key West, Florida beach resort.

The Santa Maria Suites Resort resides on the site of a long time Key West treasure. Everything is completely original in homage to our historic designation, the original facade and the restaurant remain intact. Key West Beach Resort vacation rental homes are not the best choice for everyone-sometimes a bit more panache is in order. The contemporary furnishings and appointments of our retro-inspired guest reception area combine historical significance with a fashion-forward élan. We challenge you to find other Key West resorts and hotels with more style and elegance.

Guest suites with private balconies and terraces enclose a secret garden sanctuary. The clever attention-to-detail extends to each of our stunning two-bedroom guest suites. The kitchen amenities alone are enough to inspire your culinary flair but you certainly will not be left wanting for amazing Key West dining options. Dove® candies on your pillow at turn-down service, Bath & Body Works® bath products and full concierge services are other elegant perks you'll remember long after you've returned home.

Our location is perfect for exploring Key West - just one block from Duval Street and a short walk to  the Atlantic Ocean. A car isn't necessary - it's all within walking distance. If you do drive to Key West, we do offer complimentary off-street parking. For vacation rentals at Key West resorts, you shouldn't settle for anything less than the Santa Maria Suites Resort.

Please note: There is a $25.00 Resort Fee collected at check in. Parking, wireless internet, smoothies, bottled water, turndown with muffins, chocolate and ice cream.

  • Concierge
  • Lounge/Bar
  • Fitness Center
  • Parking - Self
  • Wheelchair Access
  • 24 hour front desk
  • Cable/Satellite TV
  • Non-Smoking Facility
  • Free local telephone calls
  • Swimming Pool - Outdoor Heated
  • Internet Access - Free Public Access

Sanitization Standards and Procedures

  • Acrylic shield between guests and staff in main contact areas
  • Bed sheets and towels are washed at a temperature of at least 60°C/140°F
  • Commonly-touched surfaces are cleaned with disinfectant
  • Contactless check-out is available
  • Gloves are available to guests
  • Guests are provided with free hand sanitizer
  • Individually-wrapped food options are available
  • Individually-wrapped food options are available for breakfast
  • Masks are available to guests
  • Property confirms they are implementing enhanced health & safety measures
  • Property confirms they are implementing guest safety measures
  • Property is cleaned with disinfectant
  • Protective clothing is available to guests
  • Social distancing measures are in place
  • Staff temperature checks are conducted regularly
  • Staff wears personal protective equipment
  • Temperature checks are available to guests
Note: It is the responsibility of the hotel chain and/or the individual property to ensure the accuracy of the photos displayed. is not responsible for any inaccuracies in the photos. The room rates listed are for double occupancy per room unless otherwise stated and exclude tax recovery charges and service fees.